Abstract
So’nggi 10–15 yil ichida iste’mol bozorida “smart-mahsulotlar” ommalashdi va ular orasida energetik ichimliklar ayniqsa keng tarqaldi. So’nggi yillarda energetik ichimliklar iste’molining ortib borayotganini hisobga olgan holda, ular bilan bog’liq bo’lgan salbiy nojo’ya ta’sirlarning oldini olish uchun profilaktik strategiyalarni ishlab chiqish zarur. Energetik ichimliklarning surunkali iste’moli onkologik va nevrologik kasalliklarni rivojlanishiga olib kelishi mumkin. Bizning tadqiqotlarimiz shuni ko’rsatdiki, energetik ichimliklarni uzoq muddatli iste’mol qilish asab tizimi rivojlanishiga salbiy ta’sir ko’rsatib, S100 oqsili miqdorining oshishiga sabab bo’ladi. Shuning uchun gistologik tadqiqotlar bilan bir qatorda, qondagi S100 oqsili darajasini aniqlashga qaratilgan biokimyoviy tahlillar ham o’tkazildi
References
1. Ларенцова Л. И. и др. Экспериментально-клиническое изучение тенотена (антитела к мозгоспецифическому белку S-100) и возможности его применения в качестве средства премедикации на амбулаторном стоматологическом приеме //Российская стоматология. – 2008. – Т. 1. – №. 1. – С. 48-51.
2. Хакимова Г. Р. и др. Спектр фармакологических эффектов антител к белку S100 в релиз-активной форме и механизмы их реализации //Журнал неврологии и психиатрии им. CC Корсакова. – 2016. – Т. 116. – №. 4. – С. 100-113.
3. Allgöwer C. et al. Friend or foe: S100 proteins in cancer //Cancers. – 2020. – Т. 12. – №. 8. – С. 2037.
4. Caan B., Quesenberry Jr C. P., Coates A. O. Differences in fertility associated with caffeinated beverage consumption //American journal of public health. – 1998. – Т. 88. – №. 2. – С. 270-274.
5. Cerón J. J. et al. S-100 proteins: basics and applications as biomarkers in animals with special focus on calgranulins (S100A8, A9, and A12) //Biology. – 2023. – Т. 12. – №. 6. – С. 881.
6. Chen H. et al. S100 protein family in human cancer //American journal of cancer research. – 2014. – Т. 4. – №. 2. – С. 89.
7. Ejimofor C. F. et al. Estimation of Caffeine and Vitamin B-Complex (Vitamin B2, B3, B5 and B6) Constituents of Selected Energy Drinks //J. Appl. Chem. Sci. Int. – 2023. – Т. 14. – №. 1. – С. 42-48.
8. Higgins J. P., Yarlagadda S., Yang B. Cardiovascular complications of energy drinks //Beverages. – 2015. – Т. 1. – №. 2. – С. 104-126.
9. Michetti F., Massaro A., Murazio M. The nervous system-specific S-100 antigen in cerebrospinal fluid of multiple sclerosis patients //Neuroscience Letters. – 1979. – Т. 11. – №. 2. – С. 171-175.
10. Mitchell D. C. et al. Beverage caffeine intakes in the US //Food and Chemical Toxicology. – 2014. – Т. 63. – С. 136-142.
11. Petit A., Karila L., Lejoyeux M. Abuse of energy drinks: does it pose a risk? //Presse Medicale (Paris, France: 1983). – 2015. – Т. 44. – №. 3. – С. 261-270.
12. Reissig C. J., Strain E. C., Griffiths R. R. Caffeinated energy drinks—a growing problem //Drug and alcohol dependence. – 2009. – Т. 99. – №. 1-3. – С. 1-10.
13. Sanchis-Gomar F. et al. Energy drink overconsumption in adolescents: implications for arrhythmias and other cardiovascular events //Canadian Journal of Cardiology. – 2015. – Т. 31. – №. 5. – С. 572-575.
14. Toblin R. L. et al. Energy drink use in US service members after deployment: associations with mental health problems, aggression, and fatigue //Military medicine. – 2018. – Т. 183. – №. 11-12. – С. e364-e370.
15. Verster J. C., Koenig J. Caffeine intake and its sources: A review of national representative studies //Critical Reviews in Food Science and Nutrition. – 2018. – Т. 58. – №. 8. – С. 1250-1259.

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