Keywords
гипоксия
эндотелий
азот оксиди
eNOS
оксидловчи стресс
вазодилатация
нитрат
α-липой кислота
MitoQ.
How to Cite
Abstract
Қариш жараёнида эндотелиал функциянинг пасайиши гипоксияга қон томир жавобини ўзгартиради. Мақолада кекса ёшда NO биокираолишлиги, оксидловчи стресс ва митохондриал дисфункциянинг вазодилатацияга таъсири ҳамда айрим биологик фаол моддалар орқали коррекция имкониятлари таҳлил қилинди. Маълумотлар кекса шахсларда эндотелийга боғлиқ дилатация ва гипоксик вазодилататор жавобнинг сусайишини кўрсатади. Нитрат–нитрит–NO тизими, α-липой кислота ва митохондрияга йўналтирилган антиоксидантларнинг таъсири доза, қўллаш давомийлиги ва дастлабки гемодинамик ҳолатга боғлиқ.References
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