Keywords
polifenollar
jismoniy mashqlar
oksidlovchi stress
mushak shikastlanishi
yallig‘lanish
kurkumin
tiklanish. 1.
How to Cite
Abstract
Jadal jismoniy mashqlar oksidlovchi stress, yallig‘lanish va mushaklarning shikastlanishini keltirib chiqaradi, bu esa sport natijalari hamda tiklanish jarayoniga salbiy ta’sir ko‘rsatishi mumkin. Ushbu keng qamrovli sharh maqola mazkur fiziologik stress omillarini kamaytirishda o‘simliklardan olingan biofaol birikmalarning molekulyar mexanizmlari va klinik samaradorligi bo‘yicha mavjud ilmiy dalillarni umumlashtiradi. Maqolada o‘simlik manbalaridan olinadigan biofaol birikmalar, ayniqsa polifenollar va boshqa fitokimyoviy moddalar, redoks signalizatsiyasi, yallig‘lanish yo‘llari hamda hujayraviy stress javoblarini modulyatsiya qilish orqali qanday himoya ta’sirini namoyon etishi tahlil qilingan. Asosiy natijalar kurkumin, kversetin, resveratrol va nordon gilos (tart cherry) tarkibidagi antosianinlar kabi birikmalar mushak shikastlanishi (kreatin kinaza), oksidlovchi stress (lipid peroksidlanishi) va yallig‘lanish (IL-6, CRP) ko‘rsatkichlarini kamaytirishi mumkinligini ko‘rsatadi. Biroq, biologik o‘zlashtirilishdagi muammolar hamda klinik tadqiqotlarda kuzatilgan nomuvofiq natijalar ularning formulatsiyasini yanada takomillashtirish zarurligini ta’kidlaydi. Sharh maqola mexanistik kashfiyotlar bilan sport ovqatlanishidagi amaliy qo‘llanmalar o‘rtasidagi tafovutni tushunish uchun muhim ilmiy asos yaratadi.References
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