Abstract
Maqolada Helichrysum Mill. turkumiga mansub oʻsimliklar efir moylarining tadqiq etilganlik darajasi boʻyicha qisqacha adabiyotlar tahlili keltirildi. Oʻzbekiston va chet el florasida oʻsuvchi Helichrysum turlarining efir moylari kimyoviy tarkibi va farmakologik faolliklari qiyosiy jihatdan baholandi. Tahlil natijalariga koʻra, xorijiy turlar, ayniqsa Helichrysum italicum, nisbatan yaxshi oʻrganilgan boʻlib, ularda mono- va seskviterpen birikmalar ustunligi hamda antioksidant, antimikrob va yalligʻlanishga qarshi faollik mavjudligi aniqlangan. Shu bilan birga, Oʻzbekiston florasida tarqalgan Helichrysum arenarium, H.maracandicum, H. mussae va H. nuratavicum turlarining efir moylari kimyoviy tarkibi va dorivorlik xususiyatlari yetarlicha oʻrganilmaganligi ilmiy boʻshliq mavjudligini koʻrsatadi.
References
1. S.Qodirova, A.Xujanov. Helichrysum mill.. turkum turlarining tarqalishi //Academic research in educational sciences volume 2. special issue 2. 2021 p. 32-37
2. Хожиматов О.К. Лекарственные растения западного Тян–Шаня (в пределах республики Узбекистан): Автореф. дис. … док. биол. наук. – Ташкент, 2008. – 35 с.
3. Определител растений Средней Азии. -Ташкент, 1993.Т. Х. – С. 464-467.
4. Xolmuratov A.M. Boysun-choʻlbair togʻlarining oʻsimliklar qoplami. // Автореф. дис. … кан. биол. наук. – Ташкент, 2007. – 45 с.
5. A.N.Xujanov. Oʻzbekistonda tarqalgan Helichrysum maracandicum Popov ex Kirp. ning biologiyasi va resurslari. // Автореф. дис. … б.ф.ф.д. (PhD). Ташкент, 2020. – 45 с.6. Oʻzbekiston Respublikasi “Qizil kitobi”. 2-tomda. – Toshkent: Chinor ENK, 2009. T. 1. – 360 b.
7. A.N.Khujanov. Distribution and Current Stat Cenopopulations of Helichrysum maracandicum Popov ex Kirp. in Uzbekistan //American Journal of Plant Sciences. 2019. Vol. 10. rr. 1280–1286.
8. O.K.Khojimatov, D.T.Khamraeva, W.Rainer. An overview of Ethnomedici-nal plants of Uzbekistan. Ethnobotany Research & Applications. 2020. Rr. 1-19 http://dx.doi.org/10.32859 era.20.08.1-19.
9. Maxkamov T.X., Xujanov A.N., Xujanova D.N. Gerbariy koleksiyalari floristik tadqiqotlarda Helichrysum L. Turkumi gerbariylari tahlili // NamDU ilmiy axborotnomasi.-Namangan. 2020.№6. -B.48-56.
10. Phillips S. J., Dudík M. Modeling of species distributions with Maxent: new extensions and a comprehensive evaluation // Ecography. – 2008. – vol. 31. – №. 2. – Pp. 161-175. https://doi.org/10.1111/j.0906-7590.2008.5203.x
11. A.Gismondi, G.D.Marco, A.Canini/Helichrysum italicum (Roth) G. Don essential oil: Composition and potential antineoplastic effect/ South African Journal of Botany. Volume 133, September 2020, Pages 222-226
12. S.Afoulous, H.Ferhout, E.G.Raoelison, A.Valentin, B.Moukarzel, F.Couderc, J.Bouajila/ Helichrysum gymnocephalum Essential Oil: Chemical Composition and Cytotoxic, Antimalarial and Antioxidant Activities, Attribution of the Activity Origin by Correlations/ Molecules 2011, 16(10), P. 8273-8291; https://doi.org/10.3390/molecules16108273
13. O.A.Aiyegoro, A.I.Okoh/Preliminary phytochemical screening and In vitro antioxidant activities of the aqueous extract of Helichrysum longifolium DC/ BMC Complementary and Alternative Medicine ISSN/ 2010 Volume 10
14.V.Roussis, M.Tsoukatou, P.V.Petrakis, I.Chinou, M.Skoula, J.B.Harborne/Volatile constituents of four Helichrysum species growing in Greece/Biochemical Systematics and Ecology Volume 28, Issue 2, March 2000, Pages 163-175
15. T.Yagura, T.Motomiya, M.Ito, G.Honda, A.Iida, F.Kiuchi, H.Tokuda, H.Nishino/ Anticarcinogenic compounds in the Uzbek medicinal plant, Helichrysum maracandicum/Journal of Natural Medicines. Volume 62, (2008) P. 174–178
16. A.O.Tucker, M.J.Maciarello, D.J.Charles, J.E.Simon/ Volatile Leaf Oil of the Curry Plant [Helichrysum italicum (Roth) G. Don subsp. italicum] and Dwarf Curry Plant [subsp. microphyllum (Willd.) Nyman] in the North American Herb Trade/Journal of Essential Oil Research Volume 9, 1997 - Issue 5 P. 583-585.
17. M.Aćimović, J.Ljujić, J.Vulić, V.D.Zheljazkov, L.Pezo, A.Varga, V.T.Šaponjac/ Helichrysum italicum (Roth) G. Don Essential Oil from Serbia: Chemical Composition, Classification and Biological Activity—May It Be a Suitable New Crop for Serbia?/ Agronomiya 2021, 11 (7), 1282; https://doi.org/10.3390/agronomy11071282
18. E.Soltanbeigi, N.Isitez, S.F.Erdogmus, S.Ozliman/ Helichrysum italicum (Roth) G. Don essential oil: composition and potential anti-tumour, anti-inflammatory, antimicrobial, and antibiofilm effects/ Journal of Biologically Active Products from Nature. Volume 15, 2025 - Issue Pages 353-368.
19. D.A.Viegas, A.P.Oliveira, L.Salgueiro, J.M.Oliveira/Helichrysum italicum: From traditional use to scientific data/Journal of Ethnopharmacology 151(1), November 2013, DOI:10.1016/j.jep.2013.11.005 R. 54-65
20.Sawilska, A.; Figas, A. Micropropagation of Helichrysum arenarium (L.) Moench. In Proceedings of the International ConferenceBiotechnology, ˇ Ceske Budejovice, Czech Republic, 15–16 February 2006; Scientific Pedagogical Publishing: ˇCeske Budˇejovice, Czech Republic, 2006; pp. 721–723.
21.Czinner, E.; Hagymasi, K.; Blazovics, A.; Kery, A.; Szoke, E. In Vitro antioxidant properties of Helichrysum arenarium (L.) Moench.J. Ethnopharmacol. 2000, 73, 437–443. [CrossRef]
22.EMA. Assessment Report on Helichrysum arenarium (L.) Moench Flos (Rapporteur: Wojciech Dymowski); European Medicines Agency:Amsterdam, The Netherlands, 2015.
23.Shikov, A.N.; Pozharitskaya, O.N.; Makarov, V.G.; Wagner, H.; Verpoorte, R.; Heinrich, M. Medicinal Plants of the RussianPharmacopoeia; Their history and applications. J. Ethnopharmacol. 2014, 154, 481–536. [CrossRef]
24. Kroeber, L. Cat’s Foot, Gnaphalium dioecum L., Antennaria dioeca, Gnaphalium arenarium, Helichrysum arenarium DC as cholagoguesand choleretics. Pharmazie 1951, 6, 615–617.
25. Szadowska, A. Pharmacology of galenic preparations and flavonoids from Helichrysum arenarium. Acta Pol. Pharm. 1962, 19,465–479.
26. Wagner, H. Pharmazeutische Biologie, Drogen und ihre Inhaltsstoffe; Gustav Fischer Verlag: Stuttgart, Germany, 1993
27. Les, F.; Venditti, A.; Cásedas, G.; Frezzac, C.; Guiso, M.; Sciubba, F.; Serafini, M.; Bianco, A.; Marta Sofía, V.; López, V. Everlastingflower (Helichrysum stoechas Moench) as a potential source of bioactive molecules with antiproliferative, antioxidant, antidiabeticand neuroprotective properties. Ind. Crops. Prod. 2017, 108, 295–302. [CrossRef
28. Mao, Z.; Gan, C.; Zhu, J.; Ma, N.; Wu, L.; Wang, L.; Wang, X. Anti-atherosclerotic activities of flavonoids from the flowers ofHelichrysum arenarium L. Moench through the pathway of anti-inflammation. Bioorg. Med. Chem. Lett. 2017, 27, 2812–2817.[CrossRef]
29. Drewes, S.E.; Van Vuuren, S.F. Antimicrobial acylphloroglucinols and dibenzyloxyflavonoids from flowers of Helichrysumgymnocomum. Phytochem. Lett. 2008, 69, 1745–1794. [CrossRef]
This work is licensed under a Creative Commons Attribution 4.0 International License.