E. CANESCENS (L.) O’SIMLIK TURIDAN AJRATIB OLINGAN 1,2-DI-O- GALLOIL--D-GLYUKOZA VA 1-O-GALLOIL-4,6-GEKSAGIDROKSIDIFENOIL- -D-GLYUKOZA POLIFENOL BIRIKMALARINING VAZORELAKSANT TA’SIRI K+-KANALLARINING ISHTIROKI
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Keywords

polifenol
1
2-di-o-galloil- β -d-glyukoza
1-o-galloil-4
6- geksagidroksidifenoil-β-d-glyukoza
aorta qon tomiri
tetroetilammoniy
K+- kanal
vazorelaksant ta'sir.

How to Cite

E. CANESCENS (L.) O’SIMLIK TURIDAN AJRATIB OLINGAN 1,2-DI-O- GALLOIL--D-GLYUKOZA VA 1-O-GALLOIL-4,6-GEKSAGIDROKSIDIFENOIL- -D-GLYUKOZA POLIFENOL BIRIKMALARINING VAZORELAKSANT TA’SIRI K+-KANALLARINING ISHTIROKI. (2026). Qo‘qon DPI. Ilmiy Xabarlar Jurnali, 8(9), 393-398. https://doi.org/10.70728/a.series.tab.v08.i09.050

Abstract

Tadqiqotda izometrik sharoitda E. Canescens (l.) oʻsimligi yer ustki qismidan ajratib olingan - 1,2-di-o-galloil- β -d-glyukoza va uning hosilasi 1-o-galloil-4,6- geksagidroksidifenoil-β-d-glyukoza polifenollarining kalamush aorta qon tomiri silliq muskul preparati qisqarish faolligiga kimyoviy strukturasiga bogʻliq vazorelaksant ta'siri oʻrganilgan. Tajribalarda 1,2-di-o-galloil-b-d-glyukoza va 1-o-galloil-4,6- geksagidroksidifenoil-β-d-glyukozaning vazorelaksant ta'siri konsentrasiya va kimyoviy strukturasiga bogʻliq boʻlib, qon tomir silliq muskul hujayralari plazmolemmasida joylashgan Ca2+ L–kanali blokadasi bilan bir qatorda sezilarli darajada K+- kanali faolligi moduyatsiyasi bilan bog‘liqligi taxmin qilindi.
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