Keywords
4-aminosalitsil kislotasi
3d metallar
aralash amidli komplekslar
sintez
tuzilish
xossalar
adabiyot sharhi
How to Cite
Abstract
3d-metallarning aminokislota hosilalari bilan koordinatsion birikmalari kimyo fanining dolzarb yo‘nalishlaridan biri bo‘lib, o‘zining xilma-xil tuzilishi, biologik faolligi va katalitik xususiyatlari bilan tadqiqotchilar e'tiborini tortmoqda. Bu birikmalar tibbiyot, farmatsevtika va materialshunoslikda katta salohiyatga ega. Ushbu adabiyot sharhining maqsadi 4-aminobutan va 4-aminosalitsil kislotalarning 3d metallar bilan aralash amidli kompleks birikmalari sintezi, tuzilishi va xossalariga oid so‘nggi ilmiy yutuqlarni tizimlashtirishdir. Tadqiqot uchun Scopus, Web of Science, Google Scholar va O‘zbekiston Respublikasi ilmiy jurnallari bazalaridan foydalanib, 2020-yildan hozirgi kungacha bo‘lgan davrni qamrab olgan tizimli adabiyot qidiruvi o‘tkazildi. Qidiruv “4-aminobutan kislotasi”, “4-aminosalitsil kislotasi”, “3d metallar”, “kompleks birikmalar”, “amidli komplekslar”, “sintez”, “tuzilish”, “xossalar”, “biologik faollik” kabi kalit so‘zlar kombinatsiyalarini o‘z ichiga oldi. O‘tkazilgan tahlil natijalariga ko‘ra, ushbu kompleks birikmalarni sintez qilish, ularning tuzilishini aniqlash va xossalarini o‘rganish bo‘yicha sezilarli yutuqlarga erishilgan. Sintez usullari metall tuzlari va ligandlarning to‘g‘ridan-to‘g‘ri o‘zaro tasirini, shuningdek, amid bog‘lanishini hosil qilish uchun kondensatsiya reaksiyalarini o‘z ichiga oladi. Tuzilishini aniqlashda rentgenostrukturaviy tahlil (XRD) va spektroskopik usullar (IQ, EPR) keng qo‘llaniladi, bu esa oktaedrik, tetraedrik yoki kvadrat-tekis koordinatsion geometriyaga ega komplekslarning aniq molekulyar va kristall tuzilishini aniqlash imkonini beradi. Ushbu tadqiqotlar yangi terapevtik vositalar, diagnostika agentlari va samarali katalizatorlar yaratish uchun muhim asos bo‘lib xizmat qiladi.References
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