Abstract
Mazkur tadqiqot Galaksifob-R metil pestitsidining homilador kalamushlar qonidagi aminotransferaza fermentlari faolligiga ta'siri hamda Sophoraflavonoside (SFL) va narsitsinning korreksiyalovchi samaradorligini baholashga bag‘ishlandi. Tajribada homiladorlikning 3- va 13-kunlarida hayvonlarga Galaksifob-R metil LD50 ning 1/10 qismi miqdorida peroral usulda yuborildi. Pestitsid ta'sirini kamaytirish maqsadida ayrim guruhlarga Sophoraflavonoside va nartsissin qo‘llanildi. Homiladorlikning 20–21-kunlarida tajriba hayvonlaridan qon namunalari olinib, biokimyoviy tekshiruvlar o‘tkazildi. Tadqiqot davomida jigar funksional holatini tavsiflovchi alaninaminotransferaza (ALT), aspartataminotransferaza (AST), umumiy oqsil va bilirubin ko‘rsatkichlari aniqlandi. Olingan natijalar pestitsid ta'sirida fermentlar faolligida o‘zgarishlar yuzaga kelishini, Sophoraflavonoside va nartsissin esa ushbu o‘zgarishlarni qisman me'yorlashtirish xususiyatiga ega ekanligini ko‘rsatdi.References
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