HOMILADOR KALAMUSHLARDA GALAKSIFOB-R METIL TA'SIRIDA AMINOTRANSFERAZA FERMENTLARI KO‘RSATKICHLARINING O‘ZGARISHI VA ULARNI FLAVONOID BIRIKMALAR BILAN KORREKSIYALASH
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Keywords

Pestitsid
oksidlovchi stress
antioksidant
galaksifob-R metil
saforoflavonosid
nartsissin
alaninaminotransferaza (ALT)
aspartataminotransferaza (AST).

How to Cite

HOMILADOR KALAMUSHLARDA GALAKSIFOB-R METIL TA’SIRIDA AMINOTRANSFERAZA FERMENTLARI KO‘RSATKICHLARINING O‘ZGARISHI VA ULARNI FLAVONOID BIRIKMALAR BILAN KORREKSIYALASH. (2026). Qo‘qon DPI. Ilmiy Xabarlar Jurnali, 8(6), 51-57. https://doi.org/10.70728/a.series.tab.v08.i06.008

Abstract

Mazkur tadqiqot Galaksifob-R metil pestitsidining homilador kalamushlar qonidagi aminotransferaza fermentlari faolligiga ta'siri hamda Sophoraflavonoside (SFL) va narsitsinning korreksiyalovchi samaradorligini baholashga bag‘ishlandi. Tajribada homiladorlikning 3- va 13-kunlarida hayvonlarga Galaksifob-R metil LD50 ning 1/10 qismi miqdorida peroral usulda yuborildi. Pestitsid ta'sirini kamaytirish maqsadida ayrim guruhlarga Sophoraflavonoside va nartsissin qo‘llanildi. Homiladorlikning 20–21-kunlarida tajriba hayvonlaridan qon namunalari olinib, biokimyoviy tekshiruvlar o‘tkazildi. Tadqiqot davomida jigar funksional holatini tavsiflovchi alaninaminotransferaza (ALT), aspartataminotransferaza (AST), umumiy oqsil va bilirubin ko‘rsatkichlari aniqlandi. Olingan natijalar pestitsid ta'sirida fermentlar faolligida o‘zgarishlar yuzaga kelishini, Sophoraflavonoside va nartsissin esa ushbu o‘zgarishlarni qisman me'yorlashtirish xususiyatiga ega ekanligini ko‘rsatdi.
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Copyright (c) 2026 Mashhura Javdatovna Abduraxmonova, Asila Solijon qizi Saloyeva (Author)