Keywords
saraton hujayralari
bakteriyalarga faollik
2- xloro-1-(3.4-dimetilfenil)propan-1-on
2-chloro-1-(2
4-dimetilfenil)propan-1-on
2-xloro-1- (2
4-dimetilfenil)propan-1-on.
How to Cite
Abstract
Atsillangan ksilol izomerlarining biologik faolliklari Pass online dasturida oʻrganildi. Shuningdek atsillangan ksilol izomerlarining bakteriyalarga qarshi faolliklari hamda turli xil kasallik keltirib chiqaruvchi ingibitorlarga qarshi faolliklarini pa va pi qiymatlari hamda ayrim saraton hujayra liniyalariga sitotoksik taʻsiri oʻrganildi, taqqoslandi va tahlil qilindi. Natijalardan maʻlum boʻldiki Atsillangan ksilol izomerlarining yuqoridagi kasalliklarga faolligi bir-biriga yaqin va baʻzi kasalliklarga va bakteriyalarga nisbatan faqat bitta izomer boshqalarga nisbatan yuqoriroq faolliklarga ega ekanligi aniqlandi.References
[1] Druzhilovskiy D. S. et al. Online resources for the prediction of biological activity of organic compounds //Russian Chemical Bulletin. – 2016. – Т. 65. – №. 2. – С. 384-393..
[2] Poroikov V. V. et al. Robustness of biological activity spectra predicting by computer program PASS for noncongeneric sets of chemical compounds //Journal of chemical information and computer sciences. – 2000. – Т. 40. – №. 6. – С. 1349-1355..
[3] Filimonov D. A. et al. Prediction of the biological activity spectra of organic compounds using the PASS online web resource //Chemistry of Heterocyclic Compounds. – 2014. – Т. 50. – №. 3. – С. 444-457..
[4] Poroikov V. V. et al. PASS biological activity spectrum predictions in the enhanced open NCI database browser //Journal of Chemical Information and Computer Sciences. – 2003. – Т. 43. – №. 1. – С. 228-236. the Extended Open NCI Database Browser // Journal of Chemical Info.
[5] Poroikov V., Filimonov D. PASS: prediction of biological activity spectra for substances //Predictive toxicology. – CRC Press, 2005. – С. 471-490..
This work is licensed under a Creative Commons Attribution 4.0 International License.
Copyright (c) 2026 Abdusattorova Zulayho, Abdushukurov Anvar, Mamatkulov Nematillo (Author)