Abstract
Mazkur maqolada Co(II), Ni(II) va Cu(II) ionlarining sefotaksim hamda amid ligandlari bilan aralash ligandli kompleks birikmalarining sintezi, tuzilishi va kimyoviy xossalari o‘rganildi. Kompleks birikmalar suvli va spirtli muhitlarda sintez qilinib, ularning tarkibi va koordinatsion holati fizik-kimyoviy usullar yordamida tahlil qilindi. Komplekslarning hosil bo‘lishida sefotaksim molekulasidagi karboksil va amin guruhlarining, amid ligandlaridagi donor atomlarning koordinatsion faolligi aniqlandi. Olingan birikmalarning eruvchanligi, termik barqarorligi, magnit xossalari hamda biologik faolligi tahlil qilindi. Tadqiqot natijalari ushbu metall komplekslarining farmatsevtik va bioanorganik kimyo sohalarida istiqbolli birikmalar ekanligini ko‘rsatadi.References
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