Abstract
Ushbu maqola Tribulus terrestris L. (temirtikan) va Glycyrrhiza glabra L. (qizilmiya) o‘simliklarining kimyoviy tarkibi, biologik faollik xususiyatlari va kombinatsion qo‘llanilishi bo'yicha jahon va o‘zbek olimlari tomonidan olib borilgan ilmiy tadqiqotlarning tizimli adabiyotlar tahliliga bag‘ishlangan. Maqolada ushbu ikki o‘simlikning biofaol komponentlari — steroid saponinlar, alkaloidlar, flavonoidlar, triterpenoid saponinlar va fenol birikmalari — qiyosiy o‘rganiladi. Ikki o‘simlikning kimyoviy ta’siri, xalq tabobatidagi kombinatsion qo‘llanilishi va yangi fitopreparat yaratish istiqbollari muhokama etiladi.References
1. Ștefanescu. R., Tero-Vescan.A., Negroiu, A., Aurica, E., & Vari, C. E. (2020). A comprehensive review of the phytochemical, pharmacological, and toxicological properties of Tribulus terrestris L. Biomolecules, 10(5), 752. https:/doi.org/10.3390/biom10050752
2. Amin, G., Shafaei, A., Javan, M., & Azarpira, N. (2015). Antibacterial activity of Tribulus terrestris and its synergistic effect with Capsella bursa-pastoris and Glycyrrhiza glabra against oral pathogens: an in-vitro study. Asian Pacific Journal of Tropical Biomedicine, 5(3), 210–215. https:/doi.org/10.1016/S2221-1691(15)30009-7
3. Chhatre, S., Nesari, T. M., Somani, G. S., Kanchan, D. M., & Sathaye, S. (2014). Phytopharmacological overview of Tribulus terrestris. Pharmacognosy Reviews, 8(15), 45–51. https://doi.org/10.4103/0973-7847.125530
4. Wahab, S., Annadurai, S., Abullais, S. S., Das, G., Ahmad, W., Ahmad, M. F., Kandasamy, G., Vasudevan, R., Ali, M. S., & Amir, M. (2021). Glycyrrhiza glabra (Licorice): A comprehensive review on its phytochemistry, biological activities, clinical evidence and toxicology. Plants, 10(12), 2751. https://doi.org/10.3390/plants10122751
5. European Medicines Agency. (2020). Assessment report on Tribulus terrestris L., herba. EMA/HMPC/533201/2019. Retrieved from https://www.ema.europa.eu
6. Fiore, C., Eisenhut, M., Krausse, R., Ragazzi, E., Pellati, D., Armanini, D., & Bielenberg, J. (2008). Antiviral effects of Glycyrrhiza species. Phytotherapy Research, 22(2), 141–148. https://doi.org/10.1002/ptr.2295
7. Wahabi, H. A., Alansary, L. A., Al-Sabban, A. H., & Glasziou, P. (2010). The effectiveness of Hibiscus sabdariffa in the treatment of hypertension: A systematic review. Phytomedicine, 17(2), 83–86. https://doi.org/10.1016/j.phymed.2009.09.002 (fon konteksti uchun)
8. Al-Ali, M., Wahbi, S., Twaij, H., & Al-Badr, A. (2003). Tribulus terrestris: Preliminary study of its diuretic and contractile effects and comparison with Zea mays. Journal of Ethnopharmacology, 85(2–3), 257–260. https://doi.org/10.1016/S0378-8741(03)00014-X
9. Dinchev, D., Janda, B., Evstatieva, L., Oleszek, W., Asenov, M. R., & Kostova, I. (2008). Distribution of steroidal saponins in Tribulus terrestris from different geographical regions. Phytochemistry, 69(1), 176–186. https://doi.org/10.1016/j.phytochem.2007.07.019
10. Asl, M. N., & Hosseinzadeh, H. (2008). Review of pharmacological effects of Glycyrrhiza sp. and its bioactive compounds. Phytotherapy Research, 22(6), 709–724. https://doi.org/10.1002/ptr.2362
11. Xoldarov, I. I. (2021). Tribulus terrestris o'simligining kimyoviy komponentlarini o‘rganish [Magistrlik dissertatsiyasi]. Farg‘ona davlat universiteti.
12. Kostova, I., & Dinchev, D. (2005). Saponins in Tribulus terrestris — Chemistry and bioactivity. Phytochemistry Reviews, 4(2–3), 111–137. https://doi.org/10.1007/s11101-005-2833-x
13. Soni, P., Siddiqui, A. A., Dwivedi, J., & Soni, V. (2012). Pharmacological properties of Tribulus terrestris Linn. (Zygophyllaceae) — A review. Advances in Biological Research, 6(6), 196–205.

This work is licensed under a Creative Commons Attribution 4.0 International License.
Copyright (c) 2026 Surayyoxon Abdusamatovna Mamatqulova, Ilyosbek Ibroximjon o'g'li Xoldarov (Author)
