Abstract
U-box turiga mansub E3 ubikutin ligazalar (PUB) o‘simliklarda oqsillar ubikunitinatsiyasi va parchalanishini boshqaruvchi muhim genlar oilasini tashkil qiladi. Ushbu genlar o‘sish, rivojlanish, ko‘payish, abiotik va biotik stressga javob va gormonal signalizatsiya jarayonlarida hal qiluvchi rol o‘ynaydi. PUB oqsillari xos U-box domeni va ko‘pincha qo‘shimcha domenlardan iborat, ularning tuzilishi va domen konfiguratsiyasi funksional turlicha xususiyatlarni ifodalaydi. Bu oilaning genlari eukariotlarda yuqori darajada konservativ bo‘lib, ular molekulyar va fiziologik javoblarni regulyatsiya qilishda muhim vosita sifatida xizmat qiladi. Shu bois, PUB genlari oilasi o‘simlik biotexnologiyasi va abiotik stressga chidamli navlarni yaratish bo‘yicha tadqiqotlarda dolzarb mavzudir. Ushbu maqolada PUB genlar oilasi vakillarini adabiyotlar asosida tahlil qildik. Ushbu ma’lumotlarning aniqlanishi kelajakda PUB genlarining boshqa genlarning ekspressiyasidagi rolini ochib beradi.References
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